Transdermal coagulation of enlarged blood vessels

Patented ultra-selective technique

The treatment of angiodysplasia, telangiectasia and varicose veins is a serious problem as the currently used methods (cryodestruction, sclerotherapy, surgical excision, and classic laser percutaneous coagulation) are not effective enough and have an increased risk of complications.

LINLINE company developed a unique technique to coagulation of enlarged blood vessels based on the creation of a new chromophore inside the treated blood vessel, which makes it possible to make laser application considerably more localized. This reduces the influence on skin pigmentation and prevents the absorption of the radiation by the normal capillaries, thus considerably reducing skin overheating and completely eliminates the risk of burns and scarring.


Port-wine stains


Spider veins

Leg veins



Hemangioma (including progressive type)

Telangiectasia in different locations


Clinical results

Anesthesia is not necessary

There is no risk of scarring

No affect on natural pigmentation

Ability of treating capillary, cavernous and progressive infantile haemangiomas

About the mechanisms of laser coagulation of blood vessels

The side effect of the selective influence on the blood vessels by laser or broadband radiation is undesirable overheating of the surrounding tissues. This is due to the following two reasons:

First – the optical properties of oxyhaemoglobin are such that in all optical range it’s impossible to choose a spectrum area in which oxyhaemoglobin would be the main chromophore. Either protein, melanin or water have a greater coefficient of absorption. Thereafter, whatever the wavelength of the radiation that is taken, the most part of the laser pulse energy will inevitably be absorbed by the surrounding tissues which will cause their overheating and can also cause scarring.

The second reason lies in the fact that, in spite of the expanded vessels, radiation is also absorbed by the normal capillaries. They, as well as the expanded vessels, contain oxyhaemoglobin, but have shorter thermal relaxation time, which leads to a fast heat outflow to the surrounding tissues and their overheating.

Solving this problem by classical methods is impossible. World statistics show that the degree of scarring during vascular disease treatment is unreasonably high.


Long-pulse coagulation

Pulsed light

Wavelength: 550-1200nm

Pulse duration: up to 500ms

Single pulse

To solve this problem, we developed the technique of influence on the blood vessels based on the following mechanisms:

First, using specific parameters of the laser pulse, we provide insignificant edema of the tissues adjacent to the vessel which squeezes blood from the small capillaries. Thus, there remains no oxyhaemoglobin in the small capillaries on the way to the expanded vessel.
Secondly, due to the specific type of laser pulse and its energy, part of oxyhaemoglobin located inside the expanded vessel turns into metahaemoglobin. During that, a lower value of laser pulse energy is used, which doesn’t lead to serious influence on melanin.
Furthermore and in view of that, metahaemoglobin is the main chromophore in the near infrared area of the spectrum. We apply radiation from this area at the expanded vessel. As a result we have a complete coagulation of the vessel without overheating the surrounding tissues.

Ultra-selective coagulation

Q-switched mode

Train of nanosecond pulses

Train duration: up to 2ms

Wavelength: 540nm + 1079nm